Scientists report chemotherapy cocktail may cause adult women to grow new egg cells

Wednesday, December 7, 2016

Chemotherapy is usually associated with a collection of side effects ranging from digestive problems to hair loss, but a study published this week in Human Reproduction demonstrated that female cancer patients may find they have something in common with much younger women in one specific area — their ovaries.

Scientists from the University of Edinburgh examined donated ovarian tissue from fourteen female cancer patients, most of whom had Hodgkin lymphoma, and compared it to tissue from healthy women. They found the samples from women who had been treated with a specific chemotherapeutic regimen known as ABVD not only contained greater numbers of dormant ova — egg cells — than those from women treated with harsher regimens but also more than samples from healthy women. ABVD is named for combining several drugs known as adriamycin, bleomycin, vinblastine, and dacarbazine.

These reproductive cells were not merely more plentiful in ABVD patients. They also appeared immature, “new” in the words of lead researcher Evelyn Telfer. This challenges the conventional belief that girls are born with all the ova they will ever have and the numbers can only go down as the cells are either used up by the reproductive cycle or succumb to damage or natural aging. However, further research is needed to confirm this. The study covered relatively few patients by scientific standards, and David Albertini of the Center for Human Reproduction in New York has suggested the cells may not actually be freshly grown. Instead, they may have always been there and were merely rendered more detectable by ABVD treatment.

The ability to grow new egg cells may have significant implications for women in Western societies, many of whom postpone childbearing to establish careers, sometimes into their late thirties or forties. However, Telfer warns against making use of these findings too soon: “There’s so much we don’t know about the ovary. We have to be very cautious about jumping to clinical applications.”

The experiments had been discussed earlier this year at the annual conference of the European Society of Human Reproduction and Embryology.

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Microsoft to track legal marijuana with new partner Kind Financial

Sunday, June 19, 2016

Microsoft announced on Thursday they are partnering with KIND Financial to help governments track the production and distribution of legal marijuana. Kind Financial, a California-based start-up company, began selling its Agrisoft Seed to Sale software three years ago. Microsoft is admitting Kind’s software on the Government portion of its Azure cloud service.

Although Kind Financial CEO David Dinenberg stressed to The Guardian they “absolutely do not touch the plant”, his company does business with growers and distributors of marijuana, as well as the governments that regulate it. State law in twenty-five US states — but not US federal law — has legalized marijuana, whether medicinally or for recreational use. Kimberly Nelson, Microsoft executive director of state and local government solutions, said they expect significant demand for technology to help states make sure cannabis distribution within their state is done according to their laws.

Kind also provides kiosks similar to automated tellers (ATMs) to facilitate marijuana transactions in dispensaries. The distribution of marijuana is often done only with cash or through machines like the ones Kind offers since many banks in the United States shy away from the marijuana industry entirely. Microsoft is not interacting with this part of Kind’s operations, however.

Microsoft and Kind will apply for contracts with state governments for their software. Currently, they have applied to Puerto Rico, a US territory, where medical marijuana has recently been made legal. BioTrackTHC, a company similar to Kind Financial, already has contracts with Washington, New Mexico, and Illinois.

Dinenberg said his company’s partnership with Microsoft is a major step in advancing the legitimacy of cannabis-related businesses.

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With A Professional Video Editing Company In Lexington Ky Your Corporate Video Will Impress

byAlma Abell

The use of video production to enhance the efforts of any corporation has been well documented. With the use of video materials, human resources departments can train new employees. When showing video footage to new business clients, these customers will be able to visualize what you are trying to say. Should your company be dealing with real estate or property of any kind, then the addition of video onto your web pages is definitely the way to impress potential buyers.

With the increased use of digital media and personal mobile devices, consumers are now able to take their own videos. While this method may be suitable for personal use, it is not the way to draw attention to your company and its services. With the equipment and expertise of a Video Editing Company in Lexington KY you can have the resources you need. Their team of editors and video directors will also be able to work with you to make sure the video footage you have gets your point across.

Another benefit to working with a Video Editing Company in Lexington KY is being able to take advantage of their many other specialties. A professional video team has the skill to perfectly perform a variety of duties. This is not only for the straight forward videos used by corporations, but for the filming of important personal events. To ascertain if this is true, all anyone needs to do is watch a professionally edited wedding video and then sit through one that has been put together by well meaning friends.

Much of this has to do with the use of professional grade equipment, and the flattering lighting used by those individuals who know how to attain correct camera angles. Your enjoyment of this video also depends on the sound quality obtained and professionals in the field have the ability to properly capture this as well. After all the footage has been assembled, skillful editing adds to its video design.

To learn more about professional video and editing services, take a look at the examples posted by First String Media. Visit the Website at Firststringmedia.com to ask for a consultation and make your own video efforts become something special.

Dutch mayors support legalisation of cannabis

Thursday, April 28, 2005

Dutch Minister Alexander Pechtold‘s radical suggestion to legalise cannabis in the Netherlands has been supported by the mayors of 20 out of 30 of the largest Dutch cities, including the mayors of Leeuwarden, Utrecht, Lelystad, Deventer, and Tilburg, according to an investigation by the Dutch newspaper Trouw. Pechtold promoted the legalisation of cannabis throughout Europe earlier this week. Pechtold’s plans are opposed by Justice Minister Piet Hein Donner however, who is advocating a tougher policy against cannabis.

The possession, consumption, and selling of cannabis, claimed by some to be less harmful and less addictive than tobacco, though not strictly legal, has been tolerated in the Netherlands for a number of years. The cultivation of cannabis, however, still poses a problem to most cities. Utrecht Mayor Annie Brouwer noted fire risks, tensions with residential areas and the illegal tapping of electricity as reasons to get cannabis cultivation to the surface, so that it can be regulated. The mayors also argued that a successful test could show Europe the benefits of legalising cannabis.

A discussion on Dutch soft drug policy is to be held later today.

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Wikinews interviews the Socialist Alliance about the upcoming Queensland State election

Monday, March 2, 2009

With a Queensland state election coming up in Australia, many minor parties will be looking to hold balance of power and making the major parties listen to what they have to say. The Socialist Alliance (SA) is one of these parties.

SA is a left-wing political party. There stated describes itself as an anti-capitalist party which believes in “a democratic society that is run by and for working people, not the tiny, greedy, destructive elite that now rules.”

It should be noted that SA is not registered for Queensland elections due to what they describe as “restrictive rules for registration.” Their candidates will run as independents. They are, however, registered for federal elections and elections in other states.

Queensland’s unicameral parliament is up for election on March 21. The election campaign will run for a total of 26 days following the issue of the writs by Governor Penelope Wensley.

Wikinews held an exclusive interview with the SA. Answering on behalf of the party was Queensland State Gonvenor Paul Benedek.

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Wikinews interviews 2020 Melbourne Lord Mayor Candidate Wayne Tseng

This article mentions the Wikimedia Foundation, one of its projects, or people related to it. Wikinews is a project of the Wikimedia Foundation.

Thursday, October 22, 2020

2020 Melbourne Lord Mayor candidate Wayne Tseng answered some questions about his campaign for the upcoming election from Wikinews. The Lord Mayor election in the Australian city is scheduled to take place this week.

Tseng runs a firm called eTranslate, which helps software developers to make the software available to the users. In the candidate’s questionnaire, Tseng said eTranslate had led to him working with all three tiers of the government. He previously belonged to the Australian Liberal Party, but has left since then, to run for mayorship as an independent candidate.

Tseng is of Chinese descent, having moved to Australia with his parents from Vietnam. Graduated in Brisbane, Tseng received his PhD in Melbourne and has been living in the city, he told Wikinews. Tseng also formed Chinese Precinct Chamber of Commerce, an organisation responsible for many “community bond building initiatives”, the Lord Mayor candidate told Wikinews.

Tseng discussed his plans for leading Melbourne, recovering from COVID-19, and “Democracy 2.0” to ensure concerns of minorities in the city were also heard. Tseng also focused on the importance of the multi-culture aspect and talked about making Melbourne the capital of the aboriginals. Tseng also explained why he thinks Melbourne is poised to be a world city by 2030.

Tseng’s deputy Lord Mayor candidate Gricol Yang is a Commercial Banker and works for ANZ Banking Group.

Currently, Sally Capp is the Lord Mayor of Melbourne, the Victorian capital. Capp was elected as an interim Lord Mayor in mid-2018 after the former Lord Mayor Robert Doyle resigned from his position after sexual assault allegations. Doyle served as the Lord Mayor of Melbourne for almost a decade since 2008.

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Delhi Food, Fun, Entertainment And Luxury

Delhi – Food, Fun, Entertainment and Luxury

by

Grubhogs

Delhi, the capital city of India, boasts the historical past but with a blend of modernity. It is one of the popular cities in the world, where one can have splendid time. Delhi, with its essence of diverse and vibrant culture, attracts tourists from all over the world. One can find eating joints, nightlife entertainment and other kind of luxury, all in one in Delhi.

[youtube]http://www.youtube.com/watch?v=LZeQNelpUmg[/youtube]

Delhi warmly welcomes everyone coming to this city and has an aura that captivates them. Being the largest metropolitan, this capital city lures people for food, shelter and money. To meet the requirements of these people, there are several restaurants. These restaurants Delhi offer scrumptious food with excellent and effective services. The city has restaurant in almost every part, where one can go for any cuisine. These restaurants Delhi are queued up not only by the locals but visitors as well. Those who wish to spend quality time with friends and family can visit any of the restaurants where quiet dinner can be enjoyed with endless delicacies. People can explore attractive places and enjoy the nightlife, as Delhi has quite a wider scope for entertainment. Apart from being an administrative hub, the city has number of pubs and clubs, where one can explore the nightlife Delhi. The nightlife Delhi is fun and happening with lively & amazing music as well as impressive crowd. The energy and enthusiasm is visible on the dance floor, where one cannot stop from having fun. Delhi’s nightlife is sure to provide music, food and unlimited fun. To create a perfect balance between work and personal health, one should seek relaxation. Spa becomes necessary in this populated city with the low concentration of fresh and clean air. For health enhancing therapies and treatments, spa Delhi is one of the rejuvenating options to go for. The refreshing treatment relaxes the body, calms the mind and rejuvenates the soul. This makes one feel as if in heaven. Fun, comfort, relaxation and luxury can all be experienced at spa Delhi. If one is in the capital city, a visit to clubs Delhi is a must. The clubs are all lined up in Delhi, where one can enjoy food, drinks and music. One must hop to any of the clubs Delhi to make the night memorable. On the whole, the heart of India, Delhi, offers numerous opportunities to the people to indulge in.

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Delhi – Food, Fun, Entertainment and Luxury

Feverfew compound gets at leukemia roots

Wednesday, February 23, 2005A compound in the common daisy-like plant feverfew kills human leukemia stem cells and could form the basis for newer, more effective drugs for the disease.

American researchers at the University of Rochester Medical Center in New York say that it could take months to develop a useable drug from the compound, parthenolide.

However, they are working to do so with chemists at the University of Kentucky who have identified a water-soluble molecule with the same properties. The US National Cancer Institute has also accepted the work into its rapid access program, which aims to speed experimental drugs into human clinical trials.

“This research is a very important step in setting the stage for future development of a new therapy for leukemia,” says Rochester researcher Craig Jordan. “We have proof that we can kill leukemia stem cells with this type of agent, and that is good news.”

Parthenolide appears to target the roots of myeloid leukemia, stem cells, while current treatments including the relatively new drug Gleevec don’t. So, “You’re pulling the weed without getting to the root,” says Jordan.

Used for centuries to fight fevers, inflammation and arthritis, feverfew earned interest from the Rochester researchers after other scientists showed that it could prevent skin cancer in animal models.

So the researchers investigated how a concentrated form of the plant component parthenolide would affect leukemia cells and normal cells.

Comparing the impact of parthenolide to the common chemotherapy drug cytarabine, they found that parthenolide selectively killed leukemia cells while sparing normal cells better.

While the findings suggest that parthenolide is a good starting point for new drugs, people with leukemia aren’t being encouraged to take high doses of feverfew as they could not take enough of the remedy to halt the disease.

The research is reported in the journal Blood.

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Furry fans flock to Further Confusion 2007

Tuesday, February 6, 2007

San Jose, California —Cell phones, cigarette lighters and glowsticks are raised in tribute as Circle of Life begins playing. Soon cheers drown out the song as the multicoloured performers appear on stage. A somewhat unusual introduction; but this is no ordinary show, and these are no ordinary attendees. This is Further Confusion, the second largest furry convention in the world.

The volunteer organizers have something to cheer about, too; Furry fans have gathered from far and wide at the DoubleTree Hotel to indulge their love of anthropomorphics, and Further Confusion’s 9th year is its largest, with a paid attendance of 2061. Their gains mirror those of Midwest FurFest, a similar convention held in Schaumburg, Illinois which grew 35% last November.

Both events feature art shows and auctions, live puppetry performance, masquerades, variety shows, games and parades, as well as panels that range from science and technology to society, sex and spirituality. Filling out the schedule, the hotel walls are lined with announcements of public and private room parties for separate groups. At night, the disco floor fills with dancing cats, dogs, and dragons.

For some, dressing up plays a large part of the convention – almost 300 brought a full costume. There are few professional mascots here, though, and only one or two of the costumes would be recognized by even the most avid cartoon-watcher. Instead, each act is planned and performed by other attendees, wearing “fursuits” of their own design. Many play off the year’s secret-agent theme — “Fur Your Eyes Only”.

Other fans seem content to restrict themselves to small accessories — perhaps some combination of paws, ears, or tail. Each fur bears a 3″x2″ badge detailing their personal character, or “fursona“. Often these characters are better-known than the people who play them.

It may seem lighthearted, even frivolous, but these conventions are becoming big business. Furry fans spent over $180,000 for lodging during the five days (Jan 18-22) of Further Confusion, and another $50,000 at the art auction. Attendees also purchase all manner of merchandise from attending dealers and artists, from on-the-spot art commissions and comic books of all ratings to prints, sculptures, and plush toys – even their very own fluffy tail.

Of course, any business has risk, and conventions can drain wallets when the sums just don’t add up. The first furry con, ConFurence in Southern California, ran successfully for over a decade, but cost its new organizer an estimated $60,000 in its last four years due to falling attendance before folding in 2003.

Anthropomorphic Arts and Education board member Peter Torkelson says that won’t happen to Further Confusion. Indeed, the convention ran a healthy surplus of almost $30,000 on $125,000 revenue last year, allowing it to pay off the last of its old debts and save for the future. As Torkelson explains: “The idea is if for some reason, say an earthquake happens, and it cripples the revenue stream, the convention will be able to survive into the next year. It does help our staff to know that we have [a reserve].”

The reserve also gives AAE the financial flexibility to fund charities throughout the year, a big part of its 501(c)(3) mandate. Over the nine years of the convention, attendees have raised over $60,000 for a variety of animal sanctuaries, wildlife refuges, and the Comic Book Legal Defense Fund.

Further Confusion’s hopes for the future are high. Chairwoman Laura Cherry noted that, unlike previous years, the board has “gone all out” for next year’s tenth anniversary, booking as many rooms as the hotel could offer. The host for 2009 has yet to be decided, but for many fans the question was not whether the current hotel will reach a limit, but when – and where – the convention will find a new home.

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Category:August 3, 2010

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